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Laboratory specialty services comprise a range of services, including, but not limited to, analytical testing services for pharmaceutical, biomedical, and other life sciences laboratories.
2'-OMe C(Ac) amidite is a Amidite reagent (Subcategory: 2'-OMe Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications - CAS: 199593-09-4 - MDL: MFCD12912403 - InChIKey: WNWUMIPFLOKTEZ-UAQIPLLRSA-N - Molecular Weight: 801.877761998 - Molecular Formula: C42H52N5O9P - Purity: ≥99% - Container Type: 30 mL Glass (20-400) - Pack Size: 1 g - Net Weight: 1 g - Gross Weight: 47.3 g - Commodity Code: 29349990 - Country Of Origin: China - IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C=C2)NC(C)=O)=O)O[C@@H]1COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OC)OCCC#N)C(C)C)C
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DiscoveryProbe Metabolism-related Compound Library contains 493 biologically active small molecules targeting diverse cellular metabolic processes These compounds are well-characterized with documented bioactivity data from agencies including FDA and EMA approvals Designed specifically for research in cellular metabolism this library encompasses inhibitors agonists or modulators aimed at metabolically relevant targets such as dehydrogenases PPAR receptors HMG-CoA reductase IDO enzymes and heat shock proteins (HSPs) Representative compounds include PPAR agonists IDO inhibitors and known HMG-CoA reductase modulators enabling researchers to dissect metabolic pathways screen for novel drug targets and explore mechanisms underlying metabolic diseases
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CTS-1027 is a potent small-molecule matrix metalloproteinase (MMP) inhibitor used for biochemical and cellular research. It exhibits sub-nanomolar activity against key MMP isoforms and is employed to probe MMP-mediated biology and validate therapeutic hypotheses in vitro and in vivo.
Sub-nanomolar potency against MMP2 (IC50 0.3 nM) and MMP13 (IC50 0.5 nM).
Greater than 1,000-fold selectivity over MMP1.
High purity suitable for research (LCMS purity 99.24%).
Molecular weight 425.88 g/mol and formula C19H20ClNO6S.
Solid, white to off-white appearance for straightforward handling.
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HR2-920-33/MembFac #33 (C9), 185 ml - 0.1 M Ammonium sulfate, 0.1 M HEPES sodium pH 7.5, 18% v/v Polyethylene glycol 400. Please note items from this supplier are non-returnable.
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HR2-917-47/Natrix 2 #47 (H11), 185 ml - 0.2 M Calcium chloride dihydrate, 0.05 M HEPES sodium pH 7.5, 28% v/v Polyethylene glycol 400, 0.002 M Spermine. Please note items from this supplier are non-returnable.
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A specialized pro-resolving mediator; increases macrophage phagocytosis of PMNs in vitro and after 24 hours in vivo in mice; decreases PMN infiltration in a zymosan-induced mouse model of inflammation at 300 ng per animal; inhibits increases in neutrophil counts in BALF and lung myeloperoxidase activity in an LPS-induced mouse model of pulmonary injury and inflammation
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Non-detergent sulfobetaine. Crystallization grade NDSB-256 for formulating screens or for optimization. Please note items from this supplier are non-returnable.
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HR2-928-C6/Grid Screen PEG/LiCl #C6, 185 ml - 0.1 M BICINE pH 9.0, 1.0 M Lithium chloride, 20% w/v Polyethylene glycol 6,000. Please note items from this supplier are non-returnable.
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HR2-944-83/Index #83 (G11), 185 ml - 0.2 M Magnesium chloride hexahydrate, 0.1 M BIS-TRIS pH 6.5, 25% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
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